Bagaimana nak bina natural sunscreen (sun callus).?

 Bagaimana nak bina natural sunscreen (sun callus).?

1) Betolkan Circadian Rhythm (filaggrin) 2) Redlight (filaggrin) 3) UVA (filaggrin-urocanic acid, melanin) 4) UVB (cathelicidin)

-Filaggrin fx utk provide physical barrier ,hydration dan penghasilan urocanic acid -Urocanic acid provid slightly low ph dan kasi photoprotection bila terdedah dgn UV -Melanin prevent DNA damage to keratinocyte -Cathelicidin promote skin regeneration

Selain itu pengambilan DHA dan Astaxanthin juga dpt menolong mengurangkan oxidative damage.

tanpa Bmal1 gene (circadian gene), Filaggrin gene berkurangan.

Infrared radiation induce Filaggrin production

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957604/

Histidine , aromatic amino acid which absorb UV light act as a precursor to formation of urocanic acid (UCA)

DHA act as a photoprotective macronutrient

https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0625.2011.01294.x

Astaxanthin protect us from UV

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073124/